Time vortex: the circadian–dopaminergic dialogue in Parkinson’s disease
Meiru Zhou, Yuxiang Xu, Ye Liu, Jing Wang, Keyuan Hou, Zhaowu An, Jianshe Wei · 2026
Read Time vortex: the circadian–dopaminergic dialogue in Parkinson’s disease by Meiru Zhou, Yuxiang Xu, Ye Liu, Jing Wang, Keyuan Hou, Zhaowu An, Jianshe Wei (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13590594.txt.
Description
Meiru Zhou and colleagues review the two-way talk between body clocks and dopamine in Parkinson's disease. Clock upset is a common non-motor feature of Parkinson's, linked both ways to disease, yet its causal role is unclear. This 2026 review looks at how clock glitches relate to early and full Parkinson's, the workings at play, and clock-based treatments.
Broken rhythms may mix with cell stress, swelling, energy failure, and protein-balance breakdown. Clock readings could aid early spotting, tracking, and timed treatments, such as light therapy or timed treatment, to improve quality of life. The authors frame the clock-dopamine talk as a hopeful frontier for Parkinson's care beyond dopamine pills alone.
Catalog record
| CREATOR | Meiru Zhou, Yuxiang Xu, Ye Liu, Jing Wang, Keyuan Hou, Zhaowu An, Jianshe Wei |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 60 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |