From sequence to timescale: a frequency-domain control-theoretic framework linking ncRNA sequence composition to epigenetic regulatory timescales
Massoud Boroujerdi · 2026
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Description
Massoud Boroujerdi proposes a 2026 framework that links the sequence makeup of non-coding RNA to the timescales of epigenetic control. Non-coding RNAs help run the genome's state: they guide chromatin change, gene silencing, and how the nucleus is built, through complexes they recruit.
Well-known long non-coding RNAs such as XIST, HOTAIR, and MALAT1 show those roles well. Yet few tools tie their letter sequence to how fast their control acts. Boroujerdi models RNA sequences as cascaded feedback systems in the frequency domain, as a molecular layer under a past model of hormone axis dynamics.
Catalog record
| CREATOR | Massoud Boroujerdi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |