Baseline Dynamics and Sleep Loss–Driven Changes of Electrocorticographic Aperiodic Properties Are Altered in Mice Lacking Neuroligin‐2
Tanya Leduc, Janine El Helou, Erika Bélanger‐Nelson, Clément Bourguignon, Jean‐Marc Lina, Valérie Mongrain · 2026
Read Baseline Dynamics and Sleep Loss–Driven Changes of Electrocorticographic Aperiodic Properties Are Altered in Mice Lacking Neuroligin‐2 by Tanya Leduc, Janine El Helou, Erika Bélanger‐Nelson, Clément Bourguignon, Jean‐Marc Lina, Valérie Mongrain (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13590249.txt.
Description
Tanya Leduc and co-authors studied brainwave patterns in mice lacking a synaptic protein in two thousand twenty-six. The protein, Neuroligin-2, shapes inhibition between brain cells and is linked to developmental disorders. The team focused on the aperiodic part of the brain signal, long treated as mere background noise.
Mice without the protein showed higher values of a decay measure across wake and sleep states, with stronger daily swings. After six hours of sleep loss, the patterns changed in ways that differed from normal mice, by state. Mutant mice also showed hypersynchronized, seizure-like events with even higher values. The findings support a role for the protein in shaping this brain activity property.
Catalog record
| CREATOR | Tanya Leduc, Janine El Helou, Erika Bélanger‐Nelson, Clément Bourguignon, Jean‐Marc Lina, Valérie Mongrain |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 87 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |