Microneedle-Enabled Exosome Therapy: From Tumor Targeting to Precision Treatment of Complex Diseases
Yuhui Fang, Hao Song, Dongxian Li, Yongyue Jiang, Kehan Zhao, Xinru Qiu, Chongguang Zhao, Xiaoyun Yu, Yumei Li, Xicheng Song · 2026
Read Microneedle-Enabled Exosome Therapy: From Tumor Targeting to Precision Treatment of Complex Diseases by Yuhui Fang, Hao Song, Dongxian Li, Yongyue Jiang, Kehan Zhao, Xinru Qiu, Chongguang Zhao, Xiaoyun Yu, Yumei Li, Xicheng Song (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13589981.txt.
Description
Yuhui Fang, Hao Song, and their co-authors review a pairing that could solve a delivery problem in medicine: exosomes carried through the skin by microneedles. Their 2026 review explains that exosomes are tiny bubbles shed by cells that ferry proteins, fats, and genetic material between cells. They are gentle on the body and shield fragile cargo, which makes them attractive as drug carriers.
Their clinical use is held back by uneven production, weak cargo loading, fast clearance from the body, and poor targeting. Microneedles pierce only the top skin layer and place the cargo exactly where needed. The review covers needle designs that dissolve, swell, freeze, or respond to signals, and how each protects and releases its exosome load.
Catalog record
| CREATOR | Yuhui Fang, Hao Song, Dongxian Li, Yongyue Jiang, Kehan Zhao, Xinru Qiu, Chongguang Zhao, Xiaoyun Yu, Yumei Li, Xicheng Song |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 59 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |