Integrative WGBS and ATAC-seq profiling reveals epigenetic and chromatin accessibility signatures associated with clutch length in goose ovaries
Hechuan Wang, Jiaxin Yin, Ke Jiang, Kexin Cong, Yunuo Liu, Weiran Yang, Xinyi Miao, Zhifeng Chen, Ying Zhang, Shengjun Liu · 2026
Read Integrative WGBS and ATAC-seq profiling reveals epigenetic and chromatin accessibility signatures associated with clutch length in goose ovaries by Hechuan Wang, Jiaxin Yin, Ke Jiang, Kexin Cong, Yunuo Liu, Weiran Yang, Xinyi Miao, Zhifeng Chen, Ying Zhang, Shengjun Liu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13589133.txt.
Description
Hechuan Wang and nine colleagues read the chemical marks on goose DNA for clues to longer egg-laying runs. A clutch is the string of eggs a goose lays without a break, and the trait's regulation was nearly unmapped. From 280 individually housed Zi geese with daily laying records, the team picked three long-clutch and three short-clutch birds and profiled their ovary tissue with two sequencing methods in 2026.
One method mapped methylation, the DNA's dimmer tags, finding over six hundred thousand differing regions; the other mapped open, readable DNA, finding about nine hundred differing stretches. Genes near the marks clustered around egg-cell support growth, hormone readiness, and the remodeling that precedes laying. One gene, RERE, was backed by both layers of evidence, and spot checks of gene activity matched the marks. The authors call the atlas a starting resource, not a finished answer.
Catalog record
| CREATOR | Hechuan Wang, Jiaxin Yin, Ke Jiang, Kexin Cong, Yunuo Liu, Weiran Yang, Xinyi Miao, Zhifeng Chen, Ying Zhang, Shengjun Liu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 57 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |