Dental pulp stem cell exosomes promote angiogenesis via the PI3K/Akt signaling pathway to treat androgenetic alopecia
Wangyu Luo, Yue Shen, Wanning Yu, Le Zhao, Miaomiao Wu, Lihua Xu, Ziyan Liu, Liu Yang, Xiaolei Zhang · 2026
Read Dental pulp stem cell exosomes promote angiogenesis via the PI3K/Akt signaling pathway to treat androgenetic alopecia by Wangyu Luo, Yue Shen, Wanning Yu, Le Zhao, Miaomiao Wu, Lihua Xu, Ziyan Liu, Liu Yang, Xiaolei Zhang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13587414.txt.
Description
Wangyu Luo and co-authors test exosomes from dental pulp stem cells as a treatment for pattern hair loss. Their 2026 study uses tiny packages that cells release to signal each other. Current drugs for this common form of hair loss often work unevenly and carry side effects.
In mice, a hormone-driven model of hair loss was treated with the exosomes or with minoxidil, a standard drug. The exosomes spurred regrowth, raised follicle density, and thickened the skin, matching the drug's effect. Cell tests showed the exosomes switched on a growth pathway and raised a vessel growth factor. Blocking that pathway weakened the effect. The team links new blood vessels around follicles to the regrowth.
Catalog record
| CREATOR | Wangyu Luo, Yue Shen, Wanning Yu, Le Zhao, Miaomiao Wu, Lihua Xu, Ziyan Liu, Liu Yang, Xiaolei Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |