Mechanism-guided radiosensitization strategies for nasopharyngeal carcinoma: Current evidence and translational perspectives (Review)
Wei Deng, Ziyun Li, Zhenhua Zhu · 2026
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Description
Wei Deng, Ziyun Li, and Zhenhua Zhu review ways to make radiation work harder against throat cancer in a 2026 paper. Nasopharyngeal carcinoma, tied to the Epstein-Barr virus, clusters in southern China and Southeast Asia. Modern radiation plus chemotherapy controls many cases, but advanced, returned, and spread disease still fails often.
Platinum chemotherapy with radiation remains the proven sensitizer. Other routes, from growth-factor blockers to immune therapy combos, hinge on picking the right patients and still need prospective proof. The review warns against mistaking drug success in spread disease for true radiation boosting. Plant-based compounds look promising in the lab but remain early ideas.
Catalog record
| CREATOR | Wei Deng, Ziyun Li, Zhenhua Zhu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |