Proteome profiling of plant Cajal bodies uncovers kingdom-specific components
Yu Zhou, Huang Tan, Axel Giudicatti, Angela Vicente-Luque, Marvin Weis, Lena Wehinger, Marina Schreidl, Irina Droste-Borel, Boris Macek, Kenneth Wayne Berendzen, Rosa Lozano-Durán · 2026
Read Proteome profiling of plant Cajal bodies uncovers kingdom-specific components by Yu Zhou, Huang Tan, Axel Giudicatti, Angela Vicente-Luque, Marvin Weis, Lena Wehinger, Marina Schreidl, Irina Droste-Borel, Boris Macek, Kenneth Wayne Berendzen, Rosa Lozano-Durán (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13586619.txt.
Description
Yu Zhou and co-authors pull off a first: isolating Cajal bodies from plant cells and listing their protein parts. Cajal bodies are soft nuclear hubs that help process RNA. Their loose, liquid-like build made them near impossible to purify, and plant versions had never been read directly.
The team blends classic purification with sorting of glowing nuclei and particles. Mass spectrometry then names the proteins riding along. A high-trust set holds a small group found only there and a larger enriched group. Some parts match known animal Cajal body proteins, while many diverge, hinting at kingdom-specific builds. Marker-based proximity tests confirm a slice of the list. The platform can now be turned on other fragile cell hubs in plants.
Catalog record
| CREATOR | Yu Zhou, Huang Tan, Axel Giudicatti, Angela Vicente-Luque, Marvin Weis, Lena Wehinger, Marina Schreidl, Irina Droste-Borel, Boris Macek, Kenneth Wayne Berendzen, Rosa Lozano-Durán |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |