Effects of a three-month exercise programme on cognition, mood and neurogenesis: the NeuroFit randomised controlled trial
Sahand Farmand, Curie Kim, Andrea Du Preez, André O. Werneck, Lucia Batzu, Dominic Pearce, Kirsten Brady, Markos Khir, Sarah Nicolas, John F. Cryan, Yvonne M. Nolan, Brendon Stubbs, Sandrine Thuret · 2026
Read Effects of a three-month exercise programme on cognition, mood and neurogenesis: the NeuroFit randomised controlled trial by Sahand Farmand, Curie Kim, Andrea Du Preez, André O. Werneck, Lucia Batzu, Dominic Pearce, Kirsten Brady, Markos Khir, Sarah Nicolas, John F. Cryan, Yvonne M. Nolan, Brendon Stubbs, Sandrine Thuret (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13586222.txt.
Description
Sahand Farmand and twelve colleagues run the NeuroFit trial, testing whether three months of exercise lifts mood, thinking, and brain growth signals in middle age. Midlife is a key window for mental change, yet prevention trials often skip it. The team recruited fifty-two healthy adults in the United Kingdom.
The live online program was led by instructors. The main target, a memory skill called pattern separation, did not improve firmly. Mood did: depressive symptom scores fell in the exercise group. Blood from exercisers also changed how lab-grown brain precursor cells multiplied, a sign the body milieu now favors new neuron growth. The authors read the pattern as staged change: mood first, biology next, cognition later.
Catalog record
| CREATOR | Sahand Farmand, Curie Kim, Andrea Du Preez, André O. Werneck, Lucia Batzu, Dominic Pearce, Kirsten Brady, Markos Khir, Sarah Nicolas, John F. Cryan, Yvonne M. Nolan, Brendon Stubbs, Sandrine Thuret |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 61 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |