Short-term postoperative neurocognitive safety and recovery profiles of remimazolam tosilate combined with flumazenil vs. propofol in cirrhotic patients undergoing endoscopic variceal treatment: a randomized controlled trial

Yanjie Chen, Xiangrong Du, Fu Shi, Na Zhu · 2026

Read Short-term postoperative neurocognitive safety and recovery profiles of remimazolam tosilate combined with flumazenil vs. propofol in cirrhotic patients undergoing endoscopic variceal treatment: a randomized controlled trial by Yanjie Chen, Xiangrong Du, Fu Shi, Na Zhu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13585984.txt.

Description

Patients with failing livers clear sedatives slowly, so the choice of drug for a short endoscopy carries real brain risk. Yanjie Chen and co-authors run a randomized trial in a 2026 study of one hundred eight cirrhotic patients having variceal treatment.

Half received propofol; half received a newer short-acting sedative paired with its own reversal agent. Thinking speed and symbol-matching tests, given before and at six and twenty-four hours after, showed no significant difference between the groups. Waking milestones, from first breath to tube removal, were also tracked. Sedation depth and recovery scores rounded out the comparison. Similar brain safety with a built-in antidote, the authors suggest, deserves a place in liver-unit practice.

Catalog record

CREATORYanjie Chen, Xiangrong Du, Fu Shi, Na Zhu
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE39 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13585984

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