Adsorption-driven Graphene Oxide SPR Biointerfaces: Coupled Thermodynamic, Kinetic, and Optical Modeling with Effective-layer Validation

Description

Sadok Kouz builds a math model of a biosensor surface in this 2026 theoretical study. The sensor uses surface plasmon resonance, a light effect that shifts when molecules pile up on a metal film. That film is coated with graphene oxide, a carbon sheet that grabs target molecules. Rather than test a finished device, the model links how much lands on the surface to how far the light signal moves.

Three landing styles were modeled, from weak to cooperative, over a prism and metal stack tuned on screen. For the middle style, the model foresaw a clear signal shift across the tested range and a detection limit that hinges on how noisy the angle reading is. Warming matched a heat-releasing process. The author is plain that these are effective, fitted numbers that still need bench tests to confirm.

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Source: https://europepmc.org/article/MED/PMC13585792