Intravenous vitamin C as micronutrient therapy in patients with sepsis or septic shock: an updated systematic review and meta-analysis of randomized controlled trials
Binrong Cai, Qian Xiao, Yiqin Xia, Xian Yu, Xiaoyan Xian, Lipeng Liu, Yue Dai, Bin He · 2026
Read Intravenous vitamin C as micronutrient therapy in patients with sepsis or septic shock: an updated systematic review and meta-analysis of randomized controlled trials by Binrong Cai, Qian Xiao, Yiqin Xia, Xian Yu, Xiaoyan Xian, Lipeng Liu, Yue Dai, Bin He (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13585581.txt.
Description
Binrong Cai and seven colleagues published a combined analysis in two thousand twenty-six on vitamin C drips for sepsis. Sepsis is a body-wide reaction to infection that can fail organs. Vitamin C has been proposed as a helper therapy, but trial results conflict.
The team pooled fourteen randomised trials with nearly two thousand patients. Vitamin C cut deaths within twenty-eight days compared with controls. The benefit came mainly from single-centre trials and vanished in multicentre ones. Patients on the vitamin also came off blood-pressure drugs sooner and improved organ scores more. Stay length and urine output did not change. No major side effects appeared. The authors grade the evidence as low quality.
Catalog record
| CREATOR | Binrong Cai, Qian Xiao, Yiqin Xia, Xian Yu, Xiaoyan Xian, Lipeng Liu, Yue Dai, Bin He |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |