Perioperative phase angle decline is associated with postoperative sarcopenia in esophageal cancer: a longitudinal cohort study with internal validation
Yuntao Hao, Yanli Wang, Yiyuan Zhao, Xiugeng Zhou, Shaolei Li, Shi Yan, Nan Wu, Xiao Dong, Liqing Gong, Ziqi Liu, Qi Yu, Zhi Peng, Yu Fang · 2026
Read Perioperative phase angle decline is associated with postoperative sarcopenia in esophageal cancer: a longitudinal cohort study with internal validation by Yuntao Hao, Yanli Wang, Yiyuan Zhao, Xiugeng Zhou, Shaolei Li, Shi Yan, Nan Wu, Xiao Dong, Liqing Gong, Ziqi Liu, Qi Yu, Zhi Peng, Yu Fang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13585515.txt.
Description
Hao and co-authors track a body-composition signal around surgery for esophageal cancer and test whether its drop warns of muscle loss. The signal is phase angle, measured one day before surgery and again one month after in ninety patients having their esophagus removed for squamous cell cancer. Patients also varied in nutrition risk and in muscle loss already present before the operation.
A steep fall in phase angle across surgery went with much higher odds of sarcopenia afterward, even after prior muscle loss and nutrition risk were taken into account. The link held up under internal checks, including bootstrap checks and a random forest comparison. By contrast, the phase angle reading taken before surgery showed no clear link to muscle loss, complications, or hospital stay. The authors stress that change over time, not one reading, carries the useful signal.
Catalog record
| CREATOR | Yuntao Hao, Yanli Wang, Yiyuan Zhao, Xiugeng Zhou, Shaolei Li, Shi Yan, Nan Wu, Xiao Dong, Liqing Gong, Ziqi Liu, Qi Yu, Zhi Peng, Yu Fang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |