Identification of favorable subgroups of pediatric high‐hyperdiploid acute lymphoblastic leukemia—A retrospective multinational study
Andishe Attarbaschi, Amir Enshaei, Saskia Sonnenberg, Chloé Arfeuille, Draga Barbaric, Lena Behrman, Anke Bergmann, Nicole Bodmer, Judith M. Boer, Myriam Campbell, Gunnar Cario, Hélène Cavé, Lydia Champezou, Sarah Elitzur, Gabriele Escherich, Hester A. de Groot‐Kruseman, Monique L. den Boer, Csongor · 2026
Read Identification of favorable subgroups of pediatric high‐hyperdiploid acute lymphoblastic leukemia—A retrospective multinational study by Andishe Attarbaschi, Amir Enshaei, Saskia Sonnenberg, Chloé Arfeuille, Draga Barbaric, Lena Behrman, Anke Bergmann, Nicole Bodmer, Judith M. Boer, Myriam Campbell, Gunnar Cario, Hélène Cavé, Lydia Champezou, Sarah Elitzur, Gabriele Escherich, Hester A. de Groot‐Kruseman, Monique L. den Boer, Csongor (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13585435.txt.
Description
Attarbaschi and co-authors pool data in 2026 from nine trials to sort which children with a common leukemia type fare best. The type carries extra copies of many chromosomes and is the most frequent gene pattern in childhood blood cancer. It shows in a quarter to a third of cases and most often ends well, yet it still feeds a large share of relapses.
The team drew on more than eleven thousand patients aged 1 to 18, treated between 1998 and 2018. About three thousand held the extra-chromosome pattern. Past groups had each drawn the best subgroup in their own way, with no shared rule. The study tests each past rule in each trial to find which one flags the largest group with the best outcome. The team bills the work as a yardstick for new groups, not a call to ease care yet.
Catalog record
| CREATOR | Andishe Attarbaschi, Amir Enshaei, Saskia Sonnenberg, Chloé Arfeuille, Draga Barbaric, Lena Behrman, Anke Bergmann, Nicole Bodmer, Judith M. Boer, Myriam Campbell, Gunnar Cario, Hélène Cavé, Lydia Champezou, Sarah Elitzur, Gabriele Escherich, Hester A. de Groot‐Kruseman, Monique L. den Boer, Csongor |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |