Prevalence and Incidence of Hereditary Angioedema: A Systematic Literature Review
Timothy J. Craig, Marc A. Riedl, Tukisa D. Smith, Ellen Kasireddy, Otto L. T. Lam, Monica R. McClain · 2026
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Description
Timothy J. Craig and colleagues pool world data on how common hereditary angioedema is in this 2026 review. The inherited condition causes sudden swelling of skin and inner passages and is often missed for years. Reports of its frequency vary a lot between places, so the team screened more than five thousand studies and kept 41 that measured diagnosed cases.
Their pooled figures put the main type at a bit over one case per hundred thousand people each year, with a rarer second type well below that. Europe and North America showed the highest pooled rates, while single reports from other regions ran lower. Ways of finding cases differed so much between countries, though, that the authors doubt the gaps are fully real, and they call for shared diagnostic rules in future counts.
Catalog record
| CREATOR | Timothy J. Craig, Marc A. Riedl, Tukisa D. Smith, Ellen Kasireddy, Otto L. T. Lam, Monica R. McClain |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41786 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |