Anion-Dependent Layered Double Hydroxide-Reinforced Gelatin Methacryloyl Hydrogels for Osteoimmunomodulation and Bone Regeneration
Zhong Wang, Mengle Shi, Hao Xu, Huanbin Huang, Jin Xing, Qinwei Gu, Siyu Wang, Jiajie Zheng · 2026
Read Anion-Dependent Layered Double Hydroxide-Reinforced Gelatin Methacryloyl Hydrogels for Osteoimmunomodulation and Bone Regeneration by Zhong Wang, Mengle Shi, Hao Xu, Huanbin Huang, Jin Xing, Qinwei Gu, Siyu Wang, Jiajie Zheng (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13585088.txt.
Description
Zhong Wang and co-authors present a 2026 study of a smart gel that helps regrow bone by calming immunity first. Large skull defects fail to heal because inflammation lingers and bone building stalls. The team's gel pairs a light-set gelatin network with layered mineral nanoparticles.
Two versions of the particles differ only in the anion parked between their layers, chloride or nitrate. Both slid into immune cells and stem cells without harm. In culture, the particles nudged macrophages toward a healing mood and pushed stem cells toward bone. Gene sequencing mapped the pathways in play. In mice with critical skull defects, the loaded gel was tested for repair. The anion choice tuned the immune-skeletal conversation, the authors argue, and with it the healing.
Catalog record
| CREATOR | Zhong Wang, Mengle Shi, Hao Xu, Huanbin Huang, Jin Xing, Qinwei Gu, Siyu Wang, Jiajie Zheng |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 74 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |