Comparison of Hyaluronic Acid Versus Enamel Matrix Derivative in the Treatment of Intrabony Periodontal Defects: A Systematic Review and Meta-Analysis
Théo Mahintach, Camille Bechina, Sofiya Galina, Assem Soueidan, Christian Verner, Xavier Struillou · 2026
Read Comparison of Hyaluronic Acid Versus Enamel Matrix Derivative in the Treatment of Intrabony Periodontal Defects: A Systematic Review and Meta-Analysis by Théo Mahintach, Camille Bechina, Sofiya Galina, Assem Soueidan, Christian Verner, Xavier Struillou (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13584719.txt.
Description
Mahintach and co-authors compare two gels used to heal deep gum defects, asking whether hyaluronic acid can match the standard enamel matrix product. Both are applied during surgery for intrabony defects, pockets where bone is lost beside a tooth root. The team searched literature by standard review rules and kept only randomized trials. Three trials qualified; results were pooled for attachment gain, pocket depth, and gum recession at twelve months.
On the main outcome, attachment gain, the acid matched the standard product within the preset fairness margin; it matched on gum recession. For pocket depth, the data could not confirm a match. The authors present hyaluronic acid as a plausible alternative while stressing how thin the evidence is. More trials are needed before the swap can be recommended with confidence. For periodontists, the review is a summary of a small but suggestive literature.
Catalog record
| CREATOR | Théo Mahintach, Camille Bechina, Sofiya Galina, Assem Soueidan, Christian Verner, Xavier Struillou |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |