Quantitation of PEMT and Kennedy Pathways in Liver Phosphatidylcholine Biosynthesis Using NMR
Ji Yun Lee, Tin Tin Manh Nguyen, Thi Ha Nguyen, Eunbyul Cho, Seungjoon Lee, Hyuk Nam Kwon, Lak Shin Jeong, Dnyandev B. Jarhad, Jin Wook Cha, Sunghyouk Park · 2026
Read Quantitation of PEMT and Kennedy Pathways in Liver Phosphatidylcholine Biosynthesis Using NMR by Ji Yun Lee, Tin Tin Manh Nguyen, Thi Ha Nguyen, Eunbyul Cho, Seungjoon Lee, Hyuk Nam Kwon, Lak Shin Jeong, Dnyandev B. Jarhad, Jin Wook Cha, Sunghyouk Park (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13584693.txt.
Description
Ji Yun Lee and co-authors wrote a 2026 paper on how the liver makes one of its key fats. That fat, a building block of cell walls, comes from two routes: a main route from choline and a backup route that remakes another fat. Knowing how much each route supplies matters for understanding liver health, but older measures needed radioactive tracers and were not very sensitive.
Their new method uses magnetic resonance, tuned to tell the two routes' products apart in one test. Feed molecules labeled with a heavy form of carbon mark each route. The team refined the pulse pattern and corrected for signal fading, so the ratio of the two routes could be read with care. The method gives lipid researchers a cleaner tool.
Catalog record
| CREATOR | Ji Yun Lee, Tin Tin Manh Nguyen, Thi Ha Nguyen, Eunbyul Cho, Seungjoon Lee, Hyuk Nam Kwon, Lak Shin Jeong, Dnyandev B. Jarhad, Jin Wook Cha, Sunghyouk Park |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |