Comparative Efficacy of Bone Defect Filler Strategies Following Lesion Debridement for Osteonecrosis of the Femoral Head: A Systematic Review and Network Meta‐Analysis

Zukang Miao, Zhiwei Pei, Bing Wang, Zemeng Hou, Jingkun Jia, Junfei Zhao, Jing Dai, Xiaolei Sun, Xinlong Ma · 2026

Read Comparative Efficacy of Bone Defect Filler Strategies Following Lesion Debridement for Osteonecrosis of the Femoral Head: A Systematic Review and Network Meta‐Analysis by Zukang Miao, Zhiwei Pei, Bing Wang, Zemeng Hou, Jingkun Jia, Junfei Zhao, Jing Dai, Xiaolei Sun, Xinlong Ma (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13584610.txt.

Description

Zukang Miao leads a team of nine authors from 2026 in a study of the fillers used after dead bone is cleaned out of a hip joint. The bone loss is called osteonecrosis of the femoral head. Surgeons scrape away the dead core and pack the space left behind. It was not clear which filler works best, as past trials most often tested just one filler against one more.

Their network meta-analysis links many treatments into one web of proof, so fillers that were never tested head to head can still be compared. The team looked at how well patients did in care and what X-ray scans showed. By ranking the whole field at once, the work can name a top choice for care. That may spare future patients a trial-and-error choice of filler.

Catalog record

CREATORZukang Miao, Zhiwei Pei, Bing Wang, Zemeng Hou, Jingkun Jia, Junfei Zhao, Jing Dai, Xiaolei Sun, Xinlong Ma
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE40 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13584610

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