Opposite network patterns of integration-segregation in psychedelic and sedated states of consciousness
Rui Dai, Hyunwoo Jang, Anthony G. Hudetz, Zirui Huang, George A. Mashour · 2026
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Description
SUMMARYUnderstanding the relationship of conscious states to large-scale brain dynamics remains a central challenge in neuroscience. Here, diverse pharmacological and physiological perturbations—including psychedelics, sleep, and propofol sedation—are used to examine integration-segregation organization of brain networks across altered states of consciousness in humans using functional MRI. Across analyses, psychedelic and sedative states exhibit a robust “mirror-image” pattern of integration and segregation.
Catalog record
| CREATOR | Rui Dai, Hyunwoo Jang, Anthony G. Hudetz, Zirui Huang, George A. Mashour |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 66 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |