Minimally invasive vs standard open carpal tunnel release: A systematic review, meta-analysis, and trial sequential analysis of randomized controlled trials

Ahmed Khaled Almarri, Yazan J Alalwani, Ammar Alsayegh, Mohammed Khder M. Alamri, Faisal Falah Alanazi, Abdulmalik Hadi AlEnazy, Daniyah Adil A. Alharbi, Nawaf Salman Almutairi, Ghayed Ahmad AlWassiah, Anna Abdulmohsen Almutlaq, Abdulmajeed Abdulaziz Alfouzan, Fadi Ibrahim Alhobayyeb, Raneem M. Turk · 2026

Read Minimally invasive vs standard open carpal tunnel release: A systematic review, meta-analysis, and trial sequential analysis of randomized controlled trials by Ahmed Khaled Almarri, Yazan J Alalwani, Ammar Alsayegh, Mohammed Khder M. Alamri, Faisal Falah Alanazi, Abdulmalik Hadi AlEnazy, Daniyah Adil A. Alharbi, Nawaf Salman Almutairi, Ghayed Ahmad AlWassiah, Anna Abdulmohsen Almutlaq, Abdulmajeed Abdulaziz Alfouzan, Fadi Ibrahim Alhobayyeb, Raneem M. Turk (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13584054.txt.

Description

Ahmed Khaled Almarri and co-authors compare two surgeries for carpal tunnel syndrome in a 2026 review. The syndrome is the most common nerve pinch disorder in the world. One surgery uses a small cut, and the other uses the standard open cut. Past trials gave mixed proof on which works better.

The team pooled ten trials with 660 randomized cases. Symptom and function scores did not differ clearly between methods. The small-cut method gave shorter scars and a faster return to work. Patients went back about ten days sooner on average. Proof quality was very low for most outcomes, though. A check on trial size says far larger trials are needed.

Catalog record

CREATORAhmed Khaled Almarri, Yazan J Alalwani, Ammar Alsayegh, Mohammed Khder M. Alamri, Faisal Falah Alanazi, Abdulmalik Hadi AlEnazy, Daniyah Adil A. Alharbi, Nawaf Salman Almutairi, Ghayed Ahmad AlWassiah, Anna Abdulmohsen Almutlaq, Abdulmajeed Abdulaziz Alfouzan, Fadi Ibrahim Alhobayyeb, Raneem M. Turk
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE69 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13584054

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