Porosity-engineered long-acting protopanaxadiol microspheres prevent CDK4/6 inhibitor-induced myelosuppression
Anan Zhang, Yunjing Zhu, Xinyu Kong, Zixu Liu, Mengxia Tan, Hongyun Yu, Guanghui Jing, Jingxin Gou, Tian Yin, Haibing He, Yu Zhang, Xuemei Zhang, Ke Liu, Peifu Xiao, Xing Tang · 2026
Read Porosity-engineered long-acting protopanaxadiol microspheres prevent CDK4/6 inhibitor-induced myelosuppression by Anan Zhang, Yunjing Zhu, Xinyu Kong, Zixu Liu, Mengxia Tan, Hongyun Yu, Guanghui Jing, Jingxin Gou, Tian Yin, Haibing He, Yu Zhang, Xuemei Zhang, Ke Liu, Peifu Xiao, Xing Tang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13584051.txt.
Description
Anan Zhang and co-authors built a long-acting drug delivery system to protect blood-forming cells during cancer treatment, in this 2026 study. Some cancer drugs lower white and red cell counts, which can force doctors to pause or cut treatment. The team loaded a plant-derived compound into tiny plastic spheres whose pores they tuned with care.
After one injection into muscle, blood levels of the compound rose fast and held steady for many days. In animal models of low blood counts, the spheres restored cell counts and revived the marrow's growth signals. Paired with cancer drugs, the system also helped treatment work better, the team reports.
Catalog record
| CREATOR | Anan Zhang, Yunjing Zhu, Xinyu Kong, Zixu Liu, Mengxia Tan, Hongyun Yu, Guanghui Jing, Jingxin Gou, Tian Yin, Haibing He, Yu Zhang, Xuemei Zhang, Ke Liu, Peifu Xiao, Xing Tang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |