Comprehensive analysis of prognostic factors in myelodysplastic syndromes with isolated deletion of chromosome 5q∗†

Maria Julia Montoro, Víctor Navarro, Pamela Acha, Claudia Haferlach, Onyee Chan, Yasuo Kubota, Felicitas Schulz, Robert Briski, Najla H Al Ali, Blanca Xicoy, Felix Lopez-Cadenas, Francesc Bosch, Anna Aguilera Romero, Manja Meggendorfer, Lea Naomi Eder, Andrés Jerez, Yu-Hung Wang, Alessia Campagna, L · 2026

Read Comprehensive analysis of prognostic factors in myelodysplastic syndromes with isolated deletion of chromosome 5q∗† by Maria Julia Montoro, Víctor Navarro, Pamela Acha, Claudia Haferlach, Onyee Chan, Yasuo Kubota, Felicitas Schulz, Robert Briski, Najla H Al Ali, Blanca Xicoy, Felix Lopez-Cadenas, Francesc Bosch, Anna Aguilera Romero, Manja Meggendorfer, Lea Naomi Eder, Andrés Jerez, Yu-Hung Wang, Alessia Campagna, L (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13583942.txt.

Description

One blood disorder, where a missing chunk of chromosome 5 sets the course, usually behaves gently, yet a quarter of patients slide into acute leukemia. Maria Julia Montoro and co-authors gather six hundred and eighty-two such patients worldwide in this 2026 study to test whether the standard risk scores work inside this special subgroup. Both the classic score and its newer molecular version were put to the test.

Nearly all patients landed in the low-risk bands, yet the scores could barely tell apart those who would do well from those who would not. The team therefore hunted the factors that did predict outcomes and built a dedicated score for this disease. The work argues that a distinct biological entity deserves its own yardstick, rather than borrowing one calibrated on mixed populations.

Catalog record

CREATORMaria Julia Montoro, Víctor Navarro, Pamela Acha, Claudia Haferlach, Onyee Chan, Yasuo Kubota, Felicitas Schulz, Robert Briski, Najla H Al Ali, Blanca Xicoy, Felix Lopez-Cadenas, Francesc Bosch, Anna Aguilera Romero, Manja Meggendorfer, Lea Naomi Eder, Andrés Jerez, Yu-Hung Wang, Alessia Campagna, L
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE39 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13583942

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