Sequencing immunotherapy in locally advanced head and neck squamous cell carcinoma: a narrative clinical-translational review
Ruey-Long Hong · 2026
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Description
Ruey-Long Hong reviews when immune therapy helps in advanced head and neck cancer, in a narrative review from 2026. Immune checkpoint drugs have entered care that aims to cure locally advanced disease. Trial results split sharply by setting, which makes timing and place the core question for clinicians.
Drugs given with strong radiation and drug therapy failed again and again on main goals. Drugs given around surgery cut distant spread, likely by priming immunity while lymph nodes stay intact. Drugs after surgery helped local control once gross disease was removed from the field. Late upkeep after firm therapy showed no gain in the trials. Hong urges routine joint use only inside trials for now.
Catalog record
| CREATOR | Ruey-Long Hong |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |