Distinct and shared multimodal neuroimaging patterns in clinical frontotemporal dementia syndromes
Irene Sintini, Neha Singh-Reilly, Farwa Ali, Joseph R Duffy, Heather M Clark, Rene L Utianski, Gabriela F Meade, Mary M Machulda, Ryota Satoh, Dennis W Dickson, Val J Lowe, Keith A Josephs, Jennifer L Whitwell · 2026
Read Distinct and shared multimodal neuroimaging patterns in clinical frontotemporal dementia syndromes by Irene Sintini, Neha Singh-Reilly, Farwa Ali, Joseph R Duffy, Heather M Clark, Rene L Utianski, Gabriela F Meade, Mary M Machulda, Ryota Satoh, Dennis W Dickson, Val J Lowe, Keith A Josephs, Jennifer L Whitwell (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13583894.txt.
Description
Irene Sintini and co-authors compare brain scans across dementia types in a 2026 study. Frontotemporal dementia comes in many clinical forms, from behavior change to speech loss, and their scan patterns overlap enough to blur diagnosis.
The team studied 400 patients across eight clinical forms plus 109 healthy peers. Each person had detailed brain and thinking tests, structural MRI scans, and two kinds of PET scan, one for tau protein and one for sugar use. Math that finds shared patterns across the scans then tested how well the combined picture sorts the syndromes apart. Clearer sorting could speed diagnosis and match patients to the right trials sooner.
Catalog record
| CREATOR | Irene Sintini, Neha Singh-Reilly, Farwa Ali, Joseph R Duffy, Heather M Clark, Rene L Utianski, Gabriela F Meade, Mary M Machulda, Ryota Satoh, Dennis W Dickson, Val J Lowe, Keith A Josephs, Jennifer L Whitwell |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 70 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |