Decreased expression of immune activator WARS1 and other pro-inflammatory mediators in type 1-like macrophages as an associated mode of action in response to fucoidan from marine brown algae
Jasmin Ostermann, Timo Gemoll, Tabea Schnüttgen, Marie-Theres Tischhöfer, Kirstin Plötze-Martin, Jonas Fleckner, Karl-Ludwig Bruchhage, Susanne Alban, Ralph Pries · 2026
Read Decreased expression of immune activator WARS1 and other pro-inflammatory mediators in type 1-like macrophages as an associated mode of action in response to fucoidan from marine brown algae by Jasmin Ostermann, Timo Gemoll, Tabea Schnüttgen, Marie-Theres Tischhöfer, Kirstin Plötze-Martin, Jonas Fleckner, Karl-Ludwig Bruchhage, Susanne Alban, Ralph Pries (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13583666.txt.
Description
Jasmin Ostermann and co-authors probe how seaweed sugars calm immune cells in a 2026 study. Macrophages steer body defense; their hot form drives long burn ills when it runs wild. Brown algae yield fucoidans, sulfur sugars with broad calm marks. The team read full protein maps of lab-grown hot and calm macrophages under four algae sugars. One brown alga's sugar led the set. Its strength fell as chains were cut short.
That lead sugar cut a set of hot marks in the cells. A gene named WARS1, an immune spark, fell hard. Kin burn spills fell in step. Chain length thus grades the calm force. The authors frame the sugar's path as a drug lead for burn ills.
Catalog record
| CREATOR | Jasmin Ostermann, Timo Gemoll, Tabea Schnüttgen, Marie-Theres Tischhöfer, Kirstin Plötze-Martin, Jonas Fleckner, Karl-Ludwig Bruchhage, Susanne Alban, Ralph Pries |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |