Associations between chronic placental inflammation, fetal brain development and later autism traits
Iris Menu, Lanxin Ji, Bosi Chen, Tanya Bhatia, Mark Duffy, Sofia Trapaga, Suzanne M Jacques, Faisal Qureshi, Adam Eggebrecht, Muriah D Wheelock, Christopher J Trentacosta, Moriah E Thomason · 2026
Read Associations between chronic placental inflammation, fetal brain development and later autism traits by Iris Menu, Lanxin Ji, Bosi Chen, Tanya Bhatia, Mark Duffy, Sofia Trapaga, Suzanne M Jacques, Faisal Qureshi, Adam Eggebrecht, Muriah D Wheelock, Christopher J Trentacosta, Moriah E Thomason (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13583612.txt.
Description
Menu and co-authors present a 2026 study linking placenta inflammation before birth to brain wiring in the womb and autism traits at age three. One hundred five pregnant people had fetal brain scans late in pregnancy. After birth, pathologists graded the placentas for chronic inflammation. Forty-four fetuses had been exposed.
Exposed fetuses showed altered resting brain links across ten network pairs. Frontal, cerebellar, visual, and motor regions moved most. One link, between the cerebellum and a visual area, best predicted later autism traits. Modeling suggested inflammation lowered that link, which then tracked with traits. The authors trace a prenatal path from placenta to behavior.
Catalog record
| CREATOR | Iris Menu, Lanxin Ji, Bosi Chen, Tanya Bhatia, Mark Duffy, Sofia Trapaga, Suzanne M Jacques, Faisal Qureshi, Adam Eggebrecht, Muriah D Wheelock, Christopher J Trentacosta, Moriah E Thomason |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |