JAK Inhibitors in Colchicine Resistant FMF Patients: A Case-Based Review

Farhad Salehzadeh, Rasol Molatefi, Faeze Babazadeh Khoei · 2026

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Description

Farhad Salehzadeh, Rasol Molatefi, and Faeze Babazadeh Khoei review three cases where a JAK inhibitor calmed stubborn familial Mediterranean fever, in a 2026 paper. The fever disorder usually answers to colchicine, but a small share of patients resist it or cannot take it. Biologic drugs work yet cost much and are hard to get in many places.

Three adults who had only partly answered to colchicine plus dapsone took the oral drug twice a day. Over nine to twelve months none had a single attack, and no infection, blood, clotting, or liver harm appeared. The authors back wider study of this oral route as a stand in for costly biologics.

Catalog record

CREATORFarhad Salehzadeh, Rasol Molatefi, Faeze Babazadeh Khoei
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE17 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13583211

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