Longitudinal Multifrequency MR Elastography Reveals Biomechanical Signatures of Progression in a Translational Liver Tumor Model
Justus Ramtke, Friederike Hesse, Lasse Noack, Justus Klockner, Yubei He, Yu Liu, Yanglei Wu, Robin Schmidt, Selma Saclier, Salma A S Abosabie, Tom Meyer, Richard Ruppel, Nikolaus Berndt, Michael Mülleder, Eyk Schellenberger, Nicola Beindorff, Dominik N Müller, Ingolf Sack, Jing Guo, Shraga Nahum Gol · 2026
Read Longitudinal Multifrequency MR Elastography Reveals Biomechanical Signatures of Progression in a Translational Liver Tumor Model by Justus Ramtke, Friederike Hesse, Lasse Noack, Justus Klockner, Yubei He, Yu Liu, Yanglei Wu, Robin Schmidt, Selma Saclier, Salma A S Abosabie, Tom Meyer, Richard Ruppel, Nikolaus Berndt, Michael Mülleder, Eyk Schellenberger, Nicola Beindorff, Dominik N Müller, Ingolf Sack, Jing Guo, Shraga Nahum Gol (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13583118.txt.
Description
Justus Ramtke and a large team test whether stiffness mapping can catch liver tumors earlier than standard scans. Ordinary magnetic resonance imaging spots tumors only after shape and blood flow changes show. Tissues, though, may stiffen before a tumor is visible. The team used a method sending vibrations through the liver and reading stiffness and thickness-like traits from the waves, in rabbits carrying a fast-growing liver tumor.
The rabbits had five scans over fourteen days. Tumor stiffness and the related measure rose within two to three days of implanting the tumor, well before a standard diffusion measure changed around day eleven. Lab study showed extra collagen and similar matrix material in tumors, which fits the stiffening. The authors say the method could flag liver cancer sooner and track it during treatment. The work is in animals, so human studies would come next.
Catalog record
| CREATOR | Justus Ramtke, Friederike Hesse, Lasse Noack, Justus Klockner, Yubei He, Yu Liu, Yanglei Wu, Robin Schmidt, Selma Saclier, Salma A S Abosabie, Tom Meyer, Richard Ruppel, Nikolaus Berndt, Michael Mülleder, Eyk Schellenberger, Nicola Beindorff, Dominik N Müller, Ingolf Sack, Jing Guo, Shraga Nahum Gol |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |