Zinc finger protein-associated gene signature serves as a potential predictor for prognosis and therapeutic response in lung adenocarcinoma
Mi Zou, Guangda Zheng, Yanju Bao · 2026
Read Zinc finger protein-associated gene signature serves as a potential predictor for prognosis and therapeutic response in lung adenocarcinoma by Mi Zou, Guangda Zheng, Yanju Bao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13582719.txt.
Description
Mi Zou, Guangda Zheng, and Yanju Bao build a twelve gene risk score for lung adenocarcinoma from zinc finger protein genes, in a 2026 study. These genes carry zinc gripping parts that steer cell growth and spread. Public tumor data sets were mined for shifted family members, and a survival model kept the dozen with the sharpest signal.
The score split patients into high and low risk groups with sturdy survival separation. Low risk tumors drew more immune cells and answered immune therapy better in the data. Four candidate drugs surfaced from sensitivity screens. One risk gene was pushed in lab cells and drove more malignant behavior, backing its place in the score. The authors offer the panel as a guide for sorting patients and picking treatments.
Catalog record
| CREATOR | Mi Zou, Guangda Zheng, Yanju Bao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44393 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |