Function-based personalization of dietary fiber selection enhances gut microbial fermentation: a proof-of-concept crossover trial
Ro Osawa, Jun Inoue, Itsuko Fukuda, Yasuhito Shirai, Yuzo Kodama · 2026
Read Function-based personalization of dietary fiber selection enhances gut microbial fermentation: a proof-of-concept crossover trial by Ro Osawa, Jun Inoue, Itsuko Fukuda, Yasuhito Shirai, Yuzo Kodama (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13582658.txt.
Description
Ro Osawa and four co-authors test a personal fiber picker: a lab screen that ferments a person's gut microbes against many fibers and names the best match. Their 2026 trial starts from a known puzzle, that fiber supplements help some people and not others. No proven way existed to choose a fiber ahead of time.
Eight healthy adults took both their best-match and worst-match fibers in turn. The matched fiber raised helpful gut acids over baseline at group level, while the unmatched one did not. Seven of eight people did better on their match. Yet the screen's score gap did not predict how big each person's gain would be. The authors call the results a proof of concept that needs larger trials.
Catalog record
| CREATOR | Ro Osawa, Jun Inoue, Itsuko Fukuda, Yasuhito Shirai, Yuzo Kodama |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |