Comparative outcomes of neoadjuvant immunochemotherapy versus neoadjuvant chemoradiotherapy in locally advanced thoracic esophageal squamous cell carcinoma: a target trial emulation
Zhiyu Li, Qiuxi Zhou, Qin Xie, Chenghao Wang, Lin Peng, Yongtao Han, Xuefeng Leng, Yan Miao, Qi Zhang, Wenwu He · 2026
Read Comparative outcomes of neoadjuvant immunochemotherapy versus neoadjuvant chemoradiotherapy in locally advanced thoracic esophageal squamous cell carcinoma: a target trial emulation by Zhiyu Li, Qiuxi Zhou, Qin Xie, Chenghao Wang, Lin Peng, Yongtao Han, Xuefeng Leng, Yan Miao, Qi Zhang, Wenwu He (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13582615.txt.
Description
Zhiyu Li and co-authors compare two pre-surgery plans for advanced throat cancer in a trial-style analysis. Their 2026 study covers 288 patients with locally advanced esophageal squamous cancer. One plan pairs chemo with radiation, the standard; the other pairs chemo with immune therapy.
The radiation plan shrank tumours more on first look and caused far more severe blood suppression. Weighting the groups to balance their traits erased most response gaps. Raw survival looked alike under both plans. After weighting, the immune plan pulled ahead on staying cancer-free and on cancer-specific survival. The authors treat the result as a strong lead for a real trial.
Catalog record
| CREATOR | Zhiyu Li, Qiuxi Zhou, Qin Xie, Chenghao Wang, Lin Peng, Yongtao Han, Xuefeng Leng, Yan Miao, Qi Zhang, Wenwu He |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |