Porcine interferon-alpha but not interferon-lambda inhibits replication of genotypically diverse PRRSV isolates in vitro
Samantha J. Hau, Steven G. Kellner, Nickolas Knudsen, Lillian Skidmore, Peter C. Canning, Susan L. Brockmeier · 2026
Read Porcine interferon-alpha but not interferon-lambda inhibits replication of genotypically diverse PRRSV isolates in vitro by Samantha J. Hau, Steven G. Kellner, Nickolas Knudsen, Lillian Skidmore, Peter C. Canning, Susan L. Brockmeier (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13582555.txt.
Description
Samantha Hau and five co-authors tested two immune compounds against a pig virus in the lab. Their study, from twenty twenty-six, deals with PRRS, a virus that costs pig farms vast sums each year. Control is hard since the pigs' own immune reply comes weak and late. That has been tied to low levels of interferon, a signal that puts cells on guard. The team asked if added interferon could curb the virus.
They tried pig interferon alpha and pig interferon lambda on a range of virus types in dishes. Alpha curbed growth across the types; lambda did not. Readers who fight pig disease get a lead for a drug based add on to vaccines. Lab dish proof is a first step, not a farm ready cure.
Catalog record
| CREATOR | Samantha J. Hau, Steven G. Kellner, Nickolas Knudsen, Lillian Skidmore, Peter C. Canning, Susan L. Brockmeier |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |