Evaluation of the diagnostic value of dual-time-point, multi-parameter 99mTc-PYP imaging in diagnosing Transthyretin Cardiac Amyloidosis
Jinyong Luo, Lihua Ji, Qingfei Dong, Qingqian Kong, Ting Chen, Weihong Yuan · 2026
Read Evaluation of the diagnostic value of dual-time-point, multi-parameter 99mTc-PYP imaging in diagnosing Transthyretin Cardiac Amyloidosis by Jinyong Luo, Lihua Ji, Qingfei Dong, Qingqian Kong, Ting Chen, Weihong Yuan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13582317.txt.
Description
Jinyong Luo and co-authors tested in 2026 how to time and read a nuclear scan that diagnoses amyloid buildup in the heart. Transthyretin cardiac amyloidosis stiffens the heart and is easy to miss. The tracer scan can be read by eye grading, by a heart-to-lung ratio, or by tomographic scoring, at one hour or three hours after injection. The team reviewed ninety-eight suspected cases against biopsy and genetic truth.
Delayed tomographic imaging at three hours won clearly, with perfect sensitivity and accuracy near ninety-seven percent. The oldest eye-grading method at one hour was the least accurate. Blood pool glow caused false positives that tomography largely removed. The authors recommend delayed SPECT/CT imaging whenever early pictures look doubtful. Their cutoffs tell labs exactly when to add the late scan.
Catalog record
| CREATOR | Jinyong Luo, Lihua Ji, Qingfei Dong, Qingqian Kong, Ting Chen, Weihong Yuan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |