The STROBE guidelines and the Αristotelian mesotes curve
George P. Chrousos, Nektaria Papadopoulou-Marketou, Panagiotis Tsiamyrtzis · 2026
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Description
George Chrousos, Nektaria Papadopoulou-Marketou, and Panagiotis Tsiamyrtzis published a 2026 commentary on how medical studies should be reported. The STROBE rules guide authors of observational studies, the kind that watch real patients rather than assign treatments. Clear reports help readers judge what a study can and cannot show.
The authors link the rules to an old idea from Aristotle: mesotes, the balanced mean between too much and too little. They argue that blind, strict use of the rules can bend results in hard cases, such as studies with no placebo group. In those spots, softer tools, like gentler fixes for many tests at once, keep reports both strict and true. A worked simulation backs the advice.
Catalog record
| CREATOR | George P. Chrousos, Nektaria Papadopoulou-Marketou, Panagiotis Tsiamyrtzis |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 66 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |