Prevalence of impaired flow-mediated epicardial vasodilation among different types of coronary flow regulation
Ines Valenta, Mohammad Alavi, Ashwin S Parihar, Sudhir Jain, Thomas Hellmut Schindler · 2026
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Description
Ines Valenta and colleagues found a paradox in heart blood flow: faulty widening of large heart arteries was most common in patients whose small-vessel function looked normal. Flow-linked widening of large heart arteries as flow rises carries diagnostic and outlook weight, but its share across small-vessel states was unclear. Their PET/CT study covered 332 patients with symptoms, split by heart-muscle flow reserve.
Faulty widening affected 34.6 percent overall, but 46.2 percent of the normal-small-vessel group, versus only 13.3 and 17.9 percent in the two abnormal groups. Nearly half of patients with symptoms and normal global flow reserve may thus carry hidden artery impairment. The authors argue that checking this gradient could sharpen outlook and guide who needs further heart testing.
Catalog record
| CREATOR | Ines Valenta, Mohammad Alavi, Ashwin S Parihar, Sudhir Jain, Thomas Hellmut Schindler |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |