Effect of SGLT2 inhibitors on mean platelet volume in heart failure with reduced ejection fraction: a real-world analysis independent of diuretic therapy
Hüseyin Orta, Cihan Aydin, Aykut Demirkiran, Ferhat Perk, Aydin Akyuz · 2026
Read Effect of SGLT2 inhibitors on mean platelet volume in heart failure with reduced ejection fraction: a real-world analysis independent of diuretic therapy by Hüseyin Orta, Cihan Aydin, Aykut Demirkiran, Ferhat Perk, Aydin Akyuz (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13582056.txt.
Description
Hüseyin Orta and colleagues track a platelet size marker in weak heart patients starting a modern drug class, in a 2026 real world study. Eighty patients with reduced pumping power were already on standard therapy when the drug was added. Blood values were read at the start and again six months later, with diuretic use counted so it could not fake the result.
Average platelet volume, a rough gauge of platelet buzz and clot risk, fell clearly over the six months. Platelet counts rose in the same window. Red cell measures drifted up without reaching firm ground, and other chemistry stayed flat. The size drop did not track the count rise person by person. The authors float platelet calming as one more route of the drug's heart benefit, pending randomized proof.
Catalog record
| CREATOR | Hüseyin Orta, Cihan Aydin, Aykut Demirkiran, Ferhat Perk, Aydin Akyuz |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26084 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |