Arginine is a protective factor for risk and prognosis of gastric cancer: an observational and Mendelian randomization study

Yuanyuan Wang, Yutong Xing, Zhitu Zhu · 2026

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Description

Yuanyuan Wang, Yutong Xing, and Zhitu Zhu published this 2026 study on amino acids and stomach cancer. Some amino acids in the blood seem to fight tumors, but their links to stomach cancer risk and outlook were unclear. The team combined genetic methods with patient data and lab tests to sort this out.

Using Mendelian randomization, they tested 22 blood amino acids against cancer risk. Arginine stood out: higher levels went with lower risk, and it alone predicted how patients fared, apart from age, sex, and stage. The team built a scoring chart that uses arginine with standard factors to forecast outcomes. Lab tests on cancer cells then probed how arginine changes cell growth and gene activity.

Catalog record

CREATORYuanyuan Wang, Yutong Xing, Zhitu Zhu
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE24 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13581860

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