RNA m6A modification-regulated ferroptosis in cancer: mechanism and therapeutic potential
Qingmiao Shi, Yangni Li, Chaonan Guan · 2026
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Description
Qingmiao Shi, Yangni Li, and Chaonan Guan review a cell death path in cancer in a 2026 paper. The path, ferroptosis, kills cells through iron driven fat damage. A common RNA tag, called m6A, can raise or lower the death line by tuning the short lived messages that set it. The review pulls that cross talk into one map.
They sort the proof by who writes, reads, or wipes the tag, and by which death module each path touches, from iron handling to fat chemistry. The cross talk also shapes how tumors resist radiation and drugs. The authors flag what blocks clinic use: tag level checks, shared test rules, and ways to hit tumors only.
Catalog record
| CREATOR | Qingmiao Shi, Yangni Li, Chaonan Guan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |