Case Report: Metachronous oncocytic and colloid carcinoma arising from pancreatic intraductal neoplasms over four decades
Maria Imperatrice, Michael Johannes Pflüger, Mari Mino-Kenudson, Carlos Fernandez-del Castillo, M. Lisa Zhang · 2026
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Description
Maria Imperatrice and co-authors report two pancreatic cancers arising eight years apart in one patient, in a 2026 case paper. Growths inside the pancreatic ducts can turn into cancers of unlike kinds. One kind is aggressive, while a second, called colloid cancer, tends to grow more slowly. A third growth type is now seen as its own entity.
The patient, a woman in her eighties, had a pancreatic cyst first seen in her forties. After decades of stability, part of the pancreas was removed in 2017 and showed an early cancer of the third type. She stayed free of disease for eight years. A new cyst in 2025 then proved to be a colloid cancer from a gut-type growth. Gene tests on the second tumour found shared drivers. The first tumour could not be sequenced, so a link between them cannot be proven.
Catalog record
| CREATOR | Maria Imperatrice, Michael Johannes Pflüger, Mari Mino-Kenudson, Carlos Fernandez-del Castillo, M. Lisa Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 19 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |