Brain-computer interface for post-stroke upper-limb recovery: a systematic review integrating clinical efficacy with neuroplasticity evidence
Yu Wu, Feilong Zhu, Qiumeng Dong, Ming Zhang · 2026
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Description
Yu Wu and co-authors review brain-computer interfaces as therapy for arms weakened by stroke. More than twenty reviews already cover whether the training works in the clinic, but few pull together what it does inside the brain. This review does both: it pools results from 35 randomized trials with 1,188 patients, and separately gathers the brain-change evidence from the same trials.
Training improved arm scores across three standard scales, with the largest gains against usual care and the smallest against sham feedback. The type of comparison mattered; the stroke stage and the feedback style did not. Twenty-two trials showed brain rewiring at several levels, from spinal cord excitability to whole-network reorganization.
Catalog record
| CREATOR | Yu Wu, Feilong Zhu, Qiumeng Dong, Ming Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |