A systematic interactome of Saccharomyces cerevisiae SET1C expands its functional landscape and identifies candidate regulatory connections
Pierre Luciano, Kihyun Park, Stephane Audebert, Luc Camoin, Carlos A Niño, Da Kyeong Park, Isabella E Maudlin, Marion Dubarry, Lara Lee, Marlene Oeffinger, Jean D Beggs, Young Hye Kim, Jaehoon Kim, Bernhard Dichtl, Vincent Geli, Andrés Aguilera, Pierre Luciano, Kihyun Park, Stephane Audebert, Luc Ca · 2026
Read A systematic interactome of Saccharomyces cerevisiae SET1C expands its functional landscape and identifies candidate regulatory connections by Pierre Luciano, Kihyun Park, Stephane Audebert, Luc Camoin, Carlos A Niño, Da Kyeong Park, Isabella E Maudlin, Marion Dubarry, Lara Lee, Marlene Oeffinger, Jean D Beggs, Young Hye Kim, Jaehoon Kim, Bernhard Dichtl, Vincent Geli, Andrés Aguilera, Pierre Luciano, Kihyun Park, Stephane Audebert, Luc Ca (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13581290.txt.
Description
Pierre Luciano and co-authors mapped in 2026 the partners of a yeast protein complex that marks genes for activity. The complex, called SET1C, tags a histone protein and guides many cell processes. Using yeast two-hybrid screens on each part of the complex, the team fished for binding partners across the cell.
The catch was wide: partners in gene control, DNA copying, cell division, and RNA handling all appeared. Several import proteins that ferry cargo into the nucleus also showed up as candidate partners. The map widens the known reach of the complex and offers fresh leads on how it is regulated.
Catalog record
| CREATOR | Pierre Luciano, Kihyun Park, Stephane Audebert, Luc Camoin, Carlos A Niño, Da Kyeong Park, Isabella E Maudlin, Marion Dubarry, Lara Lee, Marlene Oeffinger, Jean D Beggs, Young Hye Kim, Jaehoon Kim, Bernhard Dichtl, Vincent Geli, Andrés Aguilera, Pierre Luciano, Kihyun Park, Stephane Audebert, Luc Ca |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 125 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |