New Insights into the Role of Mitochondrial Dysfunction in Diabetic Kidney Disease in the Omics Era
Xiao ke Liu, Xiao lan Zhou, Wen rui Xia · 2026
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Description
Xiao ke Liu, Xiao lan Zhou, and Wen rui Xia review how failing cell power plants drive diabetic kidney disease, in a 2026 paper. The disease is a major side effect of diabetes and the top cause of kidney failure worldwide. Mitochondria, the cell's power plants, falter in this disease and stir stress and inflammation. New omics tools now read genes, proteins, and small molecules layer by layer.
Layered studies show how power plant quality control breaks down in specific kidney cells. They also reveal shifts in fuel use and immune signaling inside the kidney. The work has surfaced possible markers and drug targets. Standard kidney drugs and some compounds from Chinese medicine seem to protect partly through these same paths. The authors map where precision treatment may go next.
Catalog record
| CREATOR | Xiao ke Liu, Xiao lan Zhou, Wen rui Xia |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 57 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |