Diversity and genome engineering applications of R2 non-LTR retrotransposons
Nozhat T. Hassan, Anna E. Sheppard, David L. Adelson, Kathleen Collins · 2026
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Description
Nozhat Hassan, Anna Sheppard, David Adelson, and Kathleen Collins review R2 retrotransposons in a 2026 paper. R2 elements are jumping genes that insert at one specific site in the genome. Bird R2 systems have lately been used to add chosen genes to the human genome.
The review covers how R2 sequences are found, classified, and family-treed across animals. It weighs how those catalogs, built for evolution studies, now shape engineering work. Many recent studies used a modified R2 protein to insert cargo into genomes lacking their own R2. The authors connect basic mobility research with genome engineering practice.
Catalog record
| CREATOR | Nozhat T. Hassan, Anna E. Sheppard, David L. Adelson, Kathleen Collins |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |