Shear‐Responsive Red Blood Cell Carriers for Targeted Drug Delivery to Constricted Arteries

Danielle Nemcovsky Amar, Rukiye Tuna, Tirosh Mekler, Merav Belenkovich, Dmitry Korneyev, Yevgeniy Kreinin, Anat Glozman, Josué Sznitman, Donald E. Ingber, Zixiang Leonardo Liu, Netanel Korin · 2026

Read Shear‐Responsive Red Blood Cell Carriers for Targeted Drug Delivery to Constricted Arteries by Danielle Nemcovsky Amar, Rukiye Tuna, Tirosh Mekler, Merav Belenkovich, Dmitry Korneyev, Yevgeniy Kreinin, Anat Glozman, Josué Sznitman, Donald E. Ingber, Zixiang Leonardo Liu, Netanel Korin (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13580257.txt.

Description

Nemcovsky Amar and colleagues published a 2026 study on red blood cells as smart drug couriers. Red cells carry loads well and roam the blood for a long time. Their design lets squeezed cells spill cargo only where arteries narrow. That squeezing happens where flow speeds up through a tight spot.

Loaded cells released their cargo when pumped through narrowed artery models. Open vessels triggered no release from the same loaded cells. The sheared cells kept their skins intact and still slipped through tiny channels. Computer flow models tied release to how much cell skins stretched. Such carriers could aim clot-busting drugs at dangerous narrowings someday. Healthy cells nearby would be spared the drug's side effects.

Catalog record

CREATORDanielle Nemcovsky Amar, Rukiye Tuna, Tirosh Mekler, Merav Belenkovich, Dmitry Korneyev, Yevgeniy Kreinin, Anat Glozman, Josué Sznitman, Donald E. Ingber, Zixiang Leonardo Liu, Netanel Korin
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE49 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13580257

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