Mechanisms of antibody-dependent enhancement and its research progress in animal coronaviruses
Zhiding Zhou, Yueyue Liu, Meilin Yang, Cunyi Qiu, Jing Xia, Yong Huang, Yefei Zhou · 2026
Read Mechanisms of antibody-dependent enhancement and its research progress in animal coronaviruses by Zhiding Zhou, Yueyue Liu, Meilin Yang, Cunyi Qiu, Jing Xia, Yong Huang, Yefei Zhou (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13580011.txt.
Description
Zhiding Zhou and six colleagues organize what is known about antibodies accidentally helping coronaviruses infect, in a review from two thousand twenty-six. Antibody-dependent enhancement haunts vaccine design: yesterday's antibodies make today's infection worse, not better. Animal coronaviruses cause heavy livestock losses, yet research on enhancement in them is thin.
The team sorts enhancement mechanisms into two major categories, with five mechanistic subsets inside them. Human coronavirus evidence fills each subset as the case study, and SARS-CoV-2 is the chief source of that evidence. The frame then moves that knowledge to veterinary contexts. To grasp enhancement routes in advance could keep animal vaccines safe and stop them from backfiring in the field. The review maps this field for those who study it.
Catalog record
| CREATOR | Zhiding Zhou, Yueyue Liu, Meilin Yang, Cunyi Qiu, Jing Xia, Yong Huang, Yefei Zhou |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 69 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |