Mapping the evolutionary landscape of intestinal organoids: from self-organization biology to precision medicine
Fengni Liang, Zerong Pei, Xuemei Wang, Ke Zhang · 2026
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Description
Fengni Liang, Zerong Pei, Xuemei Wang, and Ke Zhang map forty years of gut organoid research to see where the field is heading, in a 2026 analysis. Organoids are mini gut tissues grown from stem cells that copy the real organ's folds and cell mix. Publication records from 1986 to 2025 were mined with mapping tools that trace who cites whom and which topics flare up.
The United States leads on paper count, while the Netherlands, home of the founding team, leads on citation weight. Early work chased stem cell growing recipes, then swung to modeling colon cancer and bowel inflammation. The newest flare ups point to gut on a chip devices, force sensing in tissues, and single cell readouts. The authors frame the map as a compass toward engineered, patient matched gut models.
Catalog record
| CREATOR | Fengni Liang, Zerong Pei, Xuemei Wang, Ke Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 91048 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |