Optimization of polyethylene glycol-based isolation of exosomes from mesenchymal stem cells for regenerative medicine applications
Maryam Adelipour, Hyojin Hwang, Reham M Marzouk, Mohamed A Gab-Allah, Ga Seul Lee, Jeong Hee Moon, Kee K Kim, David M Lubman, Jeongkwon Kim · 2026
Read Optimization of polyethylene glycol-based isolation of exosomes from mesenchymal stem cells for regenerative medicine applications by Maryam Adelipour, Hyojin Hwang, Reham M Marzouk, Mohamed A Gab-Allah, Ga Seul Lee, Jeong Hee Moon, Kee K Kim, David M Lubman, Jeongkwon Kim (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13579858.txt.
Description
Maryam Adelipour and colleagues tune a cheap polymer method for harvesting healing vesicles from stem cell broth, in a 2026 study. Stem cells release tiny packets called exosomes that calm immune attack and aid repair, yet pulling them out cleanly at scale has lagged. The team tried three weights of a common polymer, polyethylene glycol, which crowds the packets out of solution so they can be collected.
The middle weight won on yield and purity. Its packets measured under two hundred nanometers and carried the right surface badges. A deep scan counted hundreds of proteins and over a thousand small molecules inside, proof the cargo stayed intact. Extra rinse cycles through a sizing column stripped away stray junk. Cancer cells bathed in the packets stayed alive and, at high doses, thrived a bit more.
Catalog record
| CREATOR | Maryam Adelipour, Hyojin Hwang, Reham M Marzouk, Mohamed A Gab-Allah, Ga Seul Lee, Jeong Hee Moon, Kee K Kim, David M Lubman, Jeongkwon Kim |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 58923 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |