Oral belzutifan treatment in von hippel-lindau-associated retinal hemangioblastoma: a promising approach

Adnan Kilani, Abdelrahman Assaf, Constantin Jochem, Denise Vogt, Mona Laible, Melih Parlak, Wesam Alkabouni, Armin Wolf · 2026

Read Oral belzutifan treatment in von hippel-lindau-associated retinal hemangioblastoma: a promising approach by Adnan Kilani, Abdelrahman Assaf, Constantin Jochem, Denise Vogt, Mona Laible, Melih Parlak, Wesam Alkabouni, Armin Wolf (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13579817.txt.

Description

Kilani and seven co-authors evaluate oral belzutifan for eye tumors in von Hippel-Lindau disease, in a study from twenty twenty-six. Retinal hemangioblastomas can threaten vision through fluid and bleeding. Local therapies fail in advanced or high-risk lesions sometimes. Five patients with seven eyes receive daily belzutifan after prior treatment failure.

All largest lesions shrink, with median area reduction near fifty-eight percent. Most lesions regress by more than twenty percent overall. Fluid-related detachment resolves in three of four affected eyes. Side effects stay mostly mild to moderate and manageable. Prospective trials must confirm this systemic option's value.

Catalog record

CREATORAdnan Kilani, Abdelrahman Assaf, Constantin Jochem, Denise Vogt, Mona Laible, Melih Parlak, Wesam Alkabouni, Armin Wolf
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE57 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13579817

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