Immunohistochemical evaluation of apelin and VEGF expression in cortisol-producing adrenal adenomas

Hatice Çalişkan Burgucu, Tuğba Günler, Ethem Ömeroğlu, Yaşar Ünlü, Oğuzhan Aksu · 2026

Read Immunohistochemical evaluation of apelin and VEGF expression in cortisol-producing adrenal adenomas by Hatice Çalişkan Burgucu, Tuğba Günler, Ethem Ömeroğlu, Yaşar Ünlü, Oğuzhan Aksu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13579810.txt.

Description

Hatice Çalişkan Burgucu and co-authors study two proteins in adrenal tumors in a 2026 paper. The tumors make excess cortisol and cause Cushing syndrome. The team checked tissue levels of apelin and of a growth factor tied to blood vessel growth, then compared tumor tissue with normal adrenal cortex from controls.

The study covered 11 patients with the tumors and 15 controls, using stained tissue sections scored for both strength and share of positive cells. Apelin staining strength was clearly higher in tumor tissue, though the share of positive cells and combined scores did not differ. The strength measure alone separated the groups fairly well. The authors also checked links with hormone levels and tissue traits.

Catalog record

CREATORHatice Çalişkan Burgucu, Tuğba Günler, Ethem Ömeroğlu, Yaşar Ünlü, Oğuzhan Aksu
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE44 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13579810

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